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Do you ever notice yourself becoming unusually irritated, impatient, emotionally reactive
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or overwhelmed, only to realize hours later that a migraine is coming?
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Welcome to Migraine Heroes, a podcast for people living with chronic migraines with
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years of pain, misunderstanding and lack of answers.
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I'm Diane Ducarme.
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I've helped more than a thousand people reduce the burden of migraines and feel more in control.
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My mission in life?
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To help a million people.
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Each episode brings you grounded insight into what your body might be asking for and what
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Just to keep you fully supported, this podcast is educational.
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For diagnosis or medication, always work with your doctor.
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Now take a breath and let's dive in.
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In this episode, you will learn why irritability before a migraine is actually a neurological
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symptom, not a personality flaw or emotional weakness.
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What happens inside the brain and nervous system in the hours before an attack, causing
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you to feel emotionally on edge.
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And how to recognize these early emotional warning signs so that you can support your
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body before the migraine fully escalates.
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Now stay with me till the end because at the end of this episode, you will understand why
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pre-migraine irritability is often one of the earliest clues your nervous system is
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Now many migraine sufferers know this experience very deeply.
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So you wake up already tense, small noises suddenly annoy you, people talking feels exhausting
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and tiny inconveniences feel enormous.
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You become impatient, emotionally raw or strangely overwhelmed.
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And then later, sometimes hours later, sometimes the next day, the migraine arrives.
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And for years, many people blamed themselves for this.
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They thought, why am I so moody?
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Why am I snapping at everyone?
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Why do I suddenly feel emotionally overloaded?
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But modern neuroscience now tells us something really important is that irritability before
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migraine is often part of the migraine episode itself.
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This phase is called prodrome.
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And the prodrome can begin anywhere from several hours to two days before the headache phase.
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And researchers estimate that up to 80% of migraine sufferers experience prodrome symptoms.
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And these symptoms, they're not only physical.
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According to research published in Nature Reviews Neurology, common prodrome symptoms
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include irritability, mood changes, anxiety, fatigue, but also food cravings, neck stiffness,
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concentration difficulties, and sensory sensitivity.
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So this means that before the pain even starts, the brain is already changing.
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One key area involved is the hypothalamus.
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And the hypothalamus acts as a central control center for hormones, for sleep, for stress
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response, emotional regulation, hunger, temperature, and circadian rhythms.
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There are some brain imaging studies that were published in Brain, in the journal Brain,
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and those showed that activation of the hypothalamus before migraine pain even began.
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In other words, the migraine process starts long before the actual pain.
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And because the hypothalamus is deeply connected to emotional regulation, people may first
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experience emotional symptoms rather than pain.
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And so this explains why you may suddenly feel emotionally reactive, overstimulated,
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impatient, anxious, sensitive to conflict, or unable to tolerate normal levels of stress.
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Another major factor is neurotransmitter fluctuation.
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So before a migraine attack, chemicals like serotonin, dopamine, norepinephrine, and glutamates
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can shift dramatically.
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Serotonin especially is going to play a major role in both migraine and mood regulation.
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Low serotonin levels themselves are associated with irritability and emotional instability,
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sensory sensitivity, sleep disruption, and pain amplification.
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So researchers from the Journal of Headache and Pain have described migraine as a phenomenon
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involving altered brain excitability and neurotransmitter imbalance.
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This means that the brain is becoming more reactive to internal and external stimulation.
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So now imagine trying to navigate daily life while your nervous system is already struggling
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to regulate stress, the light, the noise, the emotion, the attention, the energy production
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So of course, irritability can has room to emerge.
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But there's another layer that many people do not realize.
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During the prodrome phase, the nervous system often shifts.
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It's going to start to shift to a heightened state of alertness and the body begins unconsciously
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prepare for overload.
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So this can create tension, emotional defensiveness, frustration, restlessness, and a reduced tolerance
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So the brain is essentially saying, something's wrong, conserve energy, keep the radar on.
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But because most people do not recognize this early phase and they continue pushing through
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work stress, social demands, multitasking screens, emotional conflicts, and overstimulation.
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And of course, if you're juggling work and you're juggling your personal life and your
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work life and your health, and you intuitively feel this is coming, you're like, wow, I have
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just a couple of hours before my system may shut down and I may have to stop everything
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But oftentimes pushing through in this phase can intensify the attack.
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And so at this stage, I'm not really trying to convince you to do things one way or another.
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I'm just encouraging you to observe, really taking a step back on these events and trying
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to see, okay, what's my best response in those moments and what is going to work for me so
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that I can alleviate my pain, I can decrease, I can de-intensify and I can reduce the intensity
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and frequency of my attacks.
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Now, interestingly, researchers have also found connections between migraine and the
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And the limbic system is the emotional processing centers of the brain.
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There was a study published in Neurology and that study showed altered activity in regions
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involved in emotional regulation and sensory integration in migraine patients.
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And this explains why emotions before migraine can feel unusually intense.
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Now here's the really important message.
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You're not bad or you're not being difficult before migraine.
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Your brain is entering a neurological event and often irritability is one of the very
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first warning lights on your brain dashboard.
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If you imagine your brain as a dashboard full of lights and connection to the rest of your
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body signaling problems, this is going to be the first light showing up before the migraine.
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Now let's turn east for a minute.
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From an Eastern medicine perspective, emotional irritability before migraine is not seen as
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It is viewed as a sign that the body's internal energy is becoming constrained, is becoming
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what is called overheated or imbalanced before the attack fully manifests physically.
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And traditional Chinese medicine has long connected migraines with the liver system.
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So in traditional Chinese medicine, the liver system is not just the physical organ.
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And I really want to emphasize on this point, it's a bit like a football team.
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You can't have a single football player who's going to end score and defend and pass.
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That's not possible.
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So in that same way, if we were taking your liver and putting it to the side, it would
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be inactive and it wouldn't do anything and very quickly it would die.
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The magic of the liver organ comes from the system, from the teamwork.
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And when traditional Chinese medicine refers to the liver system, it refers to that teamwork.
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And so metrics that you can go and verify in a lab will very rarely show problems at
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the liver organ level because the liver system is going to do everything in its power to
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put the problems as far as possible from the liver as an organ in order to preserve what's
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most important and let the problems at the outside of that system, if that makes sense.
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I hope it does because it's a really important notion.
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And so in traditional Chinese medicine, the liver represents the smooth movement of that
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energy, the emotions, the internal flow.
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When I say liver system, think liver, gallbladder, all of your female hormones, all of your mood
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hormones, your breasts, your tendons, your uterus, and a lot of your brain.
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So when the energy becomes stuck, the emotional tension builds up.
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An ancient Chinese medicine saying explains that when the liver qi does not flow, frustration
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And this is profoundly relevant for migraine sufferers.
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Many people with chronic migraine spend years suppressing stress, carrying emotional pressure,
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over-performing, staying hyper-responsible and ignoring exhaustion.
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Eventually, the body can no longer compensate.
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The internal pressure begins rising.
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In traditional Chinese medicine, this is something described as liver yang rising or
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internal heat or internal wind.
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And before the migraine arrives physically, the emotional symptoms often arrive first.
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So impatience, anger, agitation, frustration, sensitivity, or emotional explosiveness.
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Eastern medicine sees these symptoms not as emotional weakness, but as a signal that the
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nervous system is becoming overloaded.
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And there's an important physiological layer here.
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In many Eastern traditions, emotions are not separate from physical health, they are
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movements of energy within the body.
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And when life becomes too fast, or too noisy, too pressured, too emotionally in process,
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the system loses harmony.
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The body starts speaking before the pain arrives.
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And so this goes beyond the object of this podcast, but this is how toxic relationship
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can play such an important role on migraines.
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If you start to make these connections, like when you feel resentful, when you feel angry,
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that will play a role in your migraine patterns, or it can, but for most people, will.
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And we'll talk about the emotional antidotes to that later.
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Ayurveda offers another fascinating perspective in Ayurveda, irritability before migraines
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is often associated with aggravated pitta dosha.
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And pitta is linked to heat, intensity, drive, sharpness, ambition, and inflammation.
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And when pitta becomes excessive, a person may feel impatient, emotionally hot, frustrated,
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critical, overstimulated, and headache-prone.
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And look, let's face it, modern life constantly fuels this imbalance.
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Rushing, overworking, screen exposure, emotional pressure, poor sleep, irregular meals, constant
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Ayurveda teaches that when internal heat accumulates without release, it eventually erupts.
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Sometimes it's anger, sometimes it's migraine, sometimes it's both.
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There's a beautiful Eastern understanding that says, the body whispers before it screams.
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And irritability may be one of those whispers.
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Not because your body is betraying you, but because it's trying to get your attention
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before collapse arrives.
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And perhaps one of the most healing shifts is this, instead of judging yourself for becoming
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irritable, you begin listening to what your nervous system is trying to communicate.
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And over the last two weeks, I was in touch with two migraine sufferers who were both
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having very difficult and reasons in their daily lives to be very angry at situations.
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And it really impacts them strongly in their migraine patterns, especially before menstruation,
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but not only before menstruation.
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And so I really want to invite you to reflect on that and take that into account.
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The opposed emotion to anger, frustration, is actually patience and is forgiveness.
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So when you start to add some of those in your life, then try to observe, then what
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Now, what's the advice for today?
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The next time you notice sudden irritability, I'd like you to pause and ask yourself, could
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this be the beginning of a migraine?
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And if you think that might be the case, can you try to immediately reduce stimulation
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Try to dim lights, drink water, slow your pace, avoid unnecessary conflict, eat something
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nourishing, have a few positive thoughts, and give your nervous system a chance to settle.
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Many migraine sufferers only respond once the pain has arrived, but the earlier you
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recognize your body's signals, the more supported your nervous system can feel.
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Your irritability may not be the problem, it may be the warning sign.
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And remember, every small step you take moves you closer to freedom.
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You are powerful, you are resilient, and you are not alone.
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Keep rising, Migraine Hero.