Migraine Heroes
Your First Migraine: Why It Happens and How to Stop It from Becoming Chronic
Migraine TypesStressMind Body
Subscribe onBy subscribing to the Migraine Heroes Podcast on Apple or Spotify, you will receive episodes twice a week with fresh evidence-based insights.

Your First Migraine: Why It Happens and How to Stop It from Becoming Chronic

16 min

Woke up with your first migraine and don’t know why? Explore what it means when pain appears suddenly in adulthood

00:00
-16:00

Woke up with a migraine out of nowhere — and now it won’t stop?

You’re not alone. In this episode of the Migraine Heroes Podcast, we explore the confusing, frightening experience of getting your first-ever migraine, especially in adulthood. Whether it started last month or you’ve recently felt like something in your body has changed for good — this conversation is for you. Hosted by Diane Ducarme, who has helped hundreds of women break free from chronic migraine patterns, this episode unpacks the medical mystery of “why now?” with clarity and compassion.

You’ll learn: 🔹 Why first migraines can show up later in life, even if you’ve never had one before 🔹 What shifts in your nervous system, hormones, and lifestyle may be triggering this change 🔹 How trying to "fix it" fast with meds can backfire — and create chronic migraine cycles 🔹 The most overlooked root cause behind many first-time attacks

If you're overwhelmed, anxious, and afraid this might be your “new normal,” take a breath. There’s another path — and you don’t have to walk it alone.

🎧 New episodes every Monday and Wednesday

Transcript

[00:00]

Woke up with a pounding head out of nowhere?

[00:04]

Today, we dive into why migraines can suddenly appear,

[00:07]

even if you've never had one before,

[00:10]

yet it's becoming your new norm in a very scary way.

[00:16]

Migraine Heroes is a podcast for chronic migraine sufferers

[00:20]

who've seen countless doctors with no results.

[00:24]

Learn how to reduce your migraine attacks

[00:26]

without endless medications or constant sacrifices.

[00:30]

Hello, I'm Diane Ducarme.

[00:32]

I've helped over 500 people break free from migraine,

[00:35]

even after suffering for up to 60 years.

[00:39]

My mission in life?

[00:40]

To bring this relief to a million people

[00:42]

using a unique blend of Eastern medicine and Western science.

[00:50]

In this episode, you will learn

[00:51]

why a first-ever migraine can happen,

[00:54]

even in adulthood,

[00:55]

due to triggers or changes in your body systems.

[00:59]

How trying to fix it can backfire fast,

[01:02]

turning occasional pain into something chronic.

[01:05]

What practical step you can take today

[01:08]

to put an end to the chaos.

[01:10]

Stay with me until the end,

[01:12]

knowing that science will empower

[01:14]

your first lines of defense,

[01:15]

leveraging the smartness of your brain, even in pain.

[01:20]

I decided to do this episode

[01:21]

because just this morning,

[01:23]

I onboarded a woman whose first migraine attack

[01:26]

happened only four weeks ago.

[01:29]

She was in total disarray.

[01:30]

She'd already been to the emergency room a few times.

[01:33]

I want to say four out of memory,

[01:35]

even if that sounds like a lot.

[01:37]

She had seen an ophthalmologist, a GP, a neurologist,

[01:41]

had done an MRI and a CD scan.

[01:43]

And in the end, she's been told,

[01:45]

so far, it's genetic, it's your new normal,

[01:49]

and you need to accept it and to medicate.

[01:52]

Now she's 36.

[01:54]

Yes, her father has had migraines his whole life,

[01:57]

but she's asking, why me?

[01:58]

Why now?

[01:59]

What do you mean a new norm?

[02:01]

She's lost, she's confused, and more than anything,

[02:05]

she's gone from never needing any medication

[02:07]

to being on all sorts of medications in just a few weeks.

[02:12]

She felt alone and isolated.

[02:14]

She felt different from everyone else.

[02:16]

And aside from a bit too much screen time,

[02:19]

a little more stress than usual,

[02:21]

and maybe a few glasses of wine,

[02:23]

there's nothing obvious that explains

[02:24]

the excruciating pain in her brain,

[02:26]

the vision loss, the numbness in the arms and legs,

[02:29]

and the nerve pain.

[02:31]

Her husband sat on our call and listens to everything.

[02:35]

And when I meet someone like that, anyone like that,

[02:38]

it becomes my mission to get them back on their feet,

[02:42]

to help them turn this chapter into just a faint memory,

[02:46]

so she can go on living her life,

[02:48]

running the business she created

[02:50]

with her husband and her two children.

[02:53]

Now, had we not met, something would have happened,

[02:57]

because I have met her before.

[02:59]

I've met her at 36, the age she's now.

[03:02]

I've also met her at 46, at 56, at 66, at 76, and at 86,

[03:09]

each time carrying an extra decade of pain.

[03:13]

But today I feel so grateful

[03:15]

because we can reverse that trend and we can do it quickly.

[03:18]

So in this episode, I want to talk you through

[03:21]

what happened in her body, what shifted,

[03:23]

both from a Western and Eastern medicine perspective,

[03:26]

and how without even realizing it,

[03:29]

she was already on her way

[03:30]

to becoming a chronic migraine sufferer for life.

[03:35]

If that is you, in a distant memory,

[03:37]

embrace that story and put yourself back in time.

[03:40]

Know that it's never too late to heal.

[03:41]

Your body wants to and knows how to do so,

[03:45]

so that story is for you as well.

[03:49]

Now, let's start from the West.

[03:51]

What do we know here?

[03:53]

We know, first of all, that migraines are genetic.

[03:55]

There's 1 to 128 Shins lucky

[03:57]

known to be responsible for migraines.

[04:00]

And while that is super impressive, we can prove that,

[04:02]

it's also fundamentally not practical.

[04:05]

What are you going to do?

[04:06]

Thank your mom and thank your dad

[04:07]

and do a big prayer for your children and grandchildren?

[04:10]

Not quite useful.

[04:12]

The second thing that we know

[04:14]

is that because it's genetic,

[04:15]

it's 5% of boys and girls who have migraines.

[04:18]

That's logical, right?

[04:19]

Mother nature being fair.

[04:21]

However, we've noticed in the West

[04:24]

that the incidence of migraines

[04:25]

is going to triple to quadruple for women at puberty,

[04:29]

leaving 18% of women,

[04:31]

and now we even talk about 21% of women in the US,

[04:35]

having migraines.

[04:36]

So if you feel alone like Cecilia,

[04:38]

trust me on this, you are not. This

[04:41]

is just a well-guarded sort of secret,

[04:44]

one that requires intimacy

[04:45]

and a ton of unconditional empathy to be talked about.

[04:49]

The third thing that we know from the West

[04:52]

is that we have a gut-brain axis.

[04:54]

Now that starts to be a lot more pragmatic.

[04:56]

That means concretely that your brain

[04:58]

gives orders to your gut, which we've always known,

[05:02]

but now your gut can give orders to your brain as well.

[05:05]

So it means technically that with what you eat,

[05:08]

we can access your brain,

[05:10]

and it's a lot more pragmatic.

[05:11]

That was discovered and proven in the West

[05:13]

about 15 to 20 years ago,

[05:16]

and used in traditional Chinese medicine

[05:17]

for about 2,000 to 5,000 years.

[05:21]

The last thing we know from a Western perspective

[05:23]

is that we have a vagus nerve,

[05:25]

and that has been discovered a much longer time ago,

[05:28]

about 200 years ago in the West,

[05:30]

because if you dissect a body,

[05:32]

you will find the vagus nerve.

[05:33]

So imagine a tree that plants its roots

[05:35]

around your heart, around your lungs,

[05:37]

around your small, large intestine,

[05:38]

around your stomach, around your liver,

[05:40]

and forms large roots along your spine,

[05:42]

collates the hundred billion nerve cells in your body,

[05:45]

and forms a trunk in your neck.

[05:47]

It's gonna plug in your brain like an electrical car.

[05:50]

And I say that because the brain is super dense,

[05:52]

and you would hope to see all of these wires

[05:55]

to go to specific places,

[05:57]

but Mother Nature has its mysteries,

[05:59]

and those cables get into the brain via the trigeminal nerve

[06:03]

and form from a Western perspective,

[06:05]

and we have no clue as to where these wires

[06:08]

end up in the brain.

[06:10]

And I don't say that lightly.

[06:11]

At Migrant Heroes, we take care of doctors,

[06:13]

of nurses, and of pharmacists,

[06:15]

and they all agree with that statement.

[06:17]

We just don't know.

[06:18]

That's a great fun of decade ahead

[06:20]

for beautiful discoveries in neurology, formidable.

[06:24]

Meanwhile, you need help today.

[06:27]

Okay, so we have some gems and some question marks

[06:30]

from a Western perspective,

[06:32]

with four things that are useful,

[06:34]

some very pragmatic, some less.

[06:37]

In the East, they were not trying to do that.

[06:39]

They were not trying to prove things scientifically,

[06:41]

or have a name on a paper,

[06:43]

or create a company that sells pharmaceutical

[06:46]

and that has shareholders, or become very famous.

[06:49]

What they were trying to do was,

[06:50]

they were in charge of people in a village,

[06:52]

and they were trying to have people like Cecilia

[06:54]

up and about at work,

[06:55]

up and about and taking care of their families.

[06:57]

And when they were not, because they had a migraine attack,

[07:00]

well, people wouldn't look at Cecilia to blame her.

[07:03]

They'd look at the doctor for not doing a good job.

[07:06]

So what they were just trying to do

[07:07]

was to have people alive, symptom-free,

[07:10]

to be able to do the small and the large things

[07:12]

they needed to achieve in life, okay?

[07:15]

And so what they discovered over thousands of years,

[07:17]

doing this on millions and billions of people,

[07:20]

was that if you were having a number of symptoms,

[07:22]

if you were trying to remove the root cause of a symptom,

[07:25]

not only would that given symptom disappear,

[07:27]

the other symptoms that pertained to that family

[07:30]

and that root cause would disappear as well.

[07:33]

And if that person was suffering from migraines and headache,

[07:38]

and you had tackled the root cause

[07:39]

of their given migraine or headache,

[07:42]

the pain would go away as well.

[07:45]

So really early on,

[07:47]

they discovered that migraine pain

[07:49]

was more like a fire alarm, like a signal,

[07:52]

and wasn't the problem itself.

[07:54]

And what is really interesting is that in 2002,

[07:57]

Dr. Elizabeth Lauder from Harvard Medical School

[08:00]

wrote this incredible paper

[08:02]

that says, what is the genetic advantage of migraine disease?

[08:06]

And basically she poses the fact that

[08:08]

how come mother nature would have left a fifth of women

[08:12]

with a genetic predisposition for what?

[08:15]

Their membranes being cuckoo?

[08:17]

She doesn't believe that.

[08:18]

I don't believe that either.

[08:19]

So what was the genetic advantage of migraine

[08:23]

that allowed these people with migraine predisposition

[08:25]

survive over and over again?

[08:28]

And in that paper, she refers to the migraine

[08:32]

like a fire alarm, just like I do on an everyday basis.

[08:36]

Now, why would you have migraine in the first place?

[08:39]

That is the object of what I discuss with people

[08:42]

in the diagnostic call.

[08:43]

It's a 90 minutes call.

[08:45]

And this morning with Cecilia, it took me a whole two hours.

[08:47]

And I really don't mind because I think fundamentally,

[08:49]

you need to understand in plain language

[08:52]

what has happened to you and why.

[08:55]

So let me brush over some of the common

[08:57]

first migraine triggers I've seen.

[08:59]

I will brush over quickly because here,

[09:01]

there is nothing you can do retrospectively, okay?

[09:03]

However, there are many things you can do moving forward.

[09:06]

And I want to focus a bit more on that.

[09:08]

But let me list out a lot of the things that I've seen

[09:11]

were triggering that first instance of migraine.

[09:14]

I've seen trauma in childhood, a poor digestion,

[09:18]

puberty kicking in, a traumatic brain injury

[09:21]

like a concussion, excess alcohol in teenage years

[09:24]

that looked like a hangover,

[09:26]

but seems suddenly disproportionately more than others,

[09:29]

intense periods of stress, burnout,

[09:32]

post-pregnancy recovery, blood donation,

[09:35]

exposure to heavy metals, excess medication

[09:38]

for another disease, contraception,

[09:40]

a change of location of city, a divorce,

[09:44]

breastfeeding, going through perimenopause,

[09:47]

a stomach bug caught in a tropical country.

[09:50]

These are some of the things that I've seen

[09:52]

would go from the absence of migraine

[09:55]

for the gene of migraine to just declare itself.

[09:58]

So if these incidents happened to you,

[10:00]

I'm not saying that the migraine kicked in right after,

[10:03]

but that it led to a domino effect of problems

[10:06]

that subsequently led to repeated migraine attacks.

[10:10]

In the case of Cecilia, it was a mix of too much screen,

[10:14]

more stress, and wine all combined at the same time

[10:17]

that provoked a first massive aura.

[10:20]

But here's the thing, in her quest to solve the migraine,

[10:25]

in her quest to go and see experts,

[10:29]

doctors and these experts made it worse.

[10:32]

And yes, I'm a bit harsh on my language here,

[10:34]

but I'm also being very factual

[10:36]

based on everything that I've seen worldwide.

[10:39]

That aura was hammered with medication

[10:43]

and an examination in her case of the pupil

[10:46]

to dilate it, that led to massive light

[10:49]

imposed on her eyes,

[10:52]

that led to another massive migraine attack.

[10:55]

And a few emergency room visits

[10:57]

that led to a lot of migraine cocktails

[10:59]

and so more medications

[11:01]

until she was then getting migraines on a daily basis.

[11:06]

So what's with all of that?

[11:08]

Let's imagine your house starts to be on fire

[11:11]

and that your fire alarm goes on.

[11:13]

If you start running like madness to extinguish it

[11:17]

and run it in the whole house to put a ladder

[11:20]

and a hammer to hammer your alarm box,

[11:23]

because that's what you're told,

[11:25]

it is likely that you're going to make things worse.

[11:27]

Why?

[11:28]

Is because at the core of all the root causes

[11:31]

that can give migraines is your liver system.

[11:35]

You see, I speak seven languages

[11:37]

and let me explain how it relates.

[11:39]

I speak seven languages

[11:40]

and you might hear that from my accent.

[11:42]

So I have a French speaking accent.

[11:43]

It's not quite French. It comes from Belgium

[11:45]

and my mother tongue's French,

[11:47]

but in Belgium, if you only speak French,

[11:49]

you can't really have a job.

[11:51]

So you have to learn Flemish.

[11:52]

Now with French and Flemish, trust me,

[11:54]

you don't really leave your country.

[11:55]

So really quickly on, you have to add on English.

[11:58]

And I went a bit overboard and I learned seven languages,

[12:02]

but it's almost like I only speak two.

[12:04]

I speak West and I speak Mandarin.

[12:06]

And if you say liver in a West term,

[12:10]

you always designate the piece of flesh

[12:12]

below your right ribcage.

[12:13]

I promise you it's all going to make sense.

[12:16]

And if you say gan in Mandarin,

[12:17]

you do not designate that piece of flesh.

[12:20]

What you designate is the liver, the gallbladder,

[12:23]

all of your female hormones, all of your mood hormones,

[12:26]

all of your tendons, your breast, your uterus,

[12:29]

your brain, a lot of your brain,

[12:30]

your temples, your eyebrows, and the top of your head.

[12:33]

You designate your ability to detox

[12:35]

and you designate your eyes, so that aura.

[12:39]

Now, when relentlessly you are told to medicate

[12:44]

to get rid of the pain,

[12:46]

you will add more and more toxicity to your liver

[12:51]

and make the migraine worse

[12:52]

and go from being episodic to chronic.

[12:57]

So the more you will see specialists,

[13:00]

the more you are likely to medicate.

[13:02]

And the more you will medicate,

[13:04]

the more you will be in pain.

[13:07]

Now, it's proven in Western science

[13:09]

that a lot of medications give rebound migraines.

[13:12]

Like if you think of tryptamines

[13:13]

or over-the-counter medications,

[13:15]

there was also a scandal with opioids.

[13:17]

But based on the episode on thiamine and histamine,

[13:20]

now you know that antidepressants and antibiotics

[13:23]

and over-the-counter medications for migraines

[13:24]

also inhibits the breakdown of histamine

[13:27]

and therefore fuel to the fire.

[13:30]

So that is how, by trying to solve the problem,

[13:33]

you start little by little to dodge yourself

[13:35]

and to believe, hey, this might be me

[13:38]

and this might be for the rest of my life.

[13:41]

And the answer is to medicate for a lifetime.

[13:43]

And maybe I need to stop complaining

[13:46]

and stop finding solutions.

[13:47]

And maybe I am depressed and maybe I am anxious.

[13:51]

And maybe this is just life, the way it's designed for me.

[13:56]

And this is happening every day, all over the globe.

[13:59]

I am, we are at Migraine Heroes to change that.

[14:03]

We make those small miracles happen every day.

[14:06]

And so had I not met Cecilia today,

[14:08]

she would have gone in that journey of more medications

[14:11]

and more throwing more solutions at her system,

[14:14]

making her system fall into a domino effect

[14:17]

that would have become more and more complex.

[14:19]

But something in Cecilia made her believe

[14:22]

that there was something else, that something was possible,

[14:25]

that she hadn't had them for so long.

[14:27]

Why her? Why now?

[14:29]

And so my one ask today is that, you know, this is not you.

[14:35]

Being in pain is not a state.

[14:38]

Let me give you one example.

[14:40]

Let's imagine you broke your knee for a minute

[14:42]

and you go to the doctor and you say, I broke my knee.

[14:45]

And he says, I'm sorry, here are some painkillers.

[14:47]

And you thank him very much.

[14:48]

And you take the painkillers and indeed it's going better.

[14:50]

You're limping, but you're not in pain.

[14:53]

So you do that for a month.

[14:54]

And then after a month you go back

[14:55]

and he gives you another stack of painkillers.

[14:58]

And then you come back the third month

[14:59]

and he gives you another stack of painkillers.

[15:00]

At some point, you might wake up and say,

[15:02]

hey, I hope at some point you'll fix it, right?

[15:05]

Or is the plan that I have painkillers for a lifetime?

[15:07]

If your knee complains and it hurts

[15:09]

and it's logical that it hurts,

[15:11]

why would your brain be illogical?

[15:14]

So my one ask today is, no, this is not you.

[15:17]

You don't have to live a life of pain.

[15:20]

We see that over and over and over again.

[15:23]

So push that door.

[15:25]

We're here to serve you.

[15:26]

If you go on our website, margarineheroes.com,

[15:28]

you can take our margarine assessment

[15:30]

and we can meet to debrief on your profile. You

[15:32]

can understand.

[15:34]

We also know that it doesn't need

[15:36]

and doesn't have to be that hard.

[15:38]

This is your life and we want, I want you to live it.

[15:44]

And remember, every small step you take

[15:47]

moves you closer to freedom.

[15:49]

You are powerful, you are resilient,

[15:52]

and you're no longer alone.

[15:54]

Keep rising, Margarine Hero.

Originally published July 2025

Don’t miss an episode

Subscribe to the Migraine Heroes Podcast on your favorite platform and get evidence-based insights twice a week.

Back to Migraine Science

Curious about the Migraine Heroes approach?

Discover your unique Migraine Profile—a clear picture of why recovery has been difficult. This report will shed light on the complexity of your migraines and reveal your healing potential.

Take Your Free Migraine Assessment
Your First Migraine: Why It Happens and | Migraine Heroes