Migraine Heroes
Two distressed people sit back-to-back beneath a broken heart, symbolizing the end of a relationship.
Subscribe onBy subscribing to the Migraine Heroes Podcast on Apple or Spotify, you will receive episodes twice a week with fresh evidence-based insights.

Your Brain Doesn't Know the Relationship Is Over

17 min

Why can your body stay on alert after a difficult relationship ends? Explore how prolonged stress may affect sleep, pain sensitivity, and migraine.

00:00
-17:00

Episode description

Leaving a difficult relationship does not always mean your nervous system immediately feels safe.

In this episode of Migraine Heroes Podcast, host Diane Ducarme explores why the brain may stay on alert long after the relationship has ended and how that ongoing sense of danger can affect sleep, pain sensitivity, and migraine.

You’ll learn:

💡 Why your brain can keep scanning for danger even when life is calmer 💡 How prolonged emotional stress may shape sleep, pain sensitivity, and migraine patterns 💡 Why imagined danger can still create very real physical reactions in the body

Understanding that connection can help you interpret your symptoms with more clarity and begin to see what your nervous system may still be responding to.

🎧 New episodes every Monday and Wednesday

Transcript

[00:00]

You left the relationship. Why is your body still afraid?

[00:04]

Welcome to Migraine Heroes. For anyone living with migraine and wondering why nothing has

[00:09]

fully worked yet, I'm Diane Ducarme. In seven years of working with people with migraine,

[00:15]

I've learned that no two migraine stories are the same and none of them are simple. But your

[00:21]

migraine has its own patterns. Here we look at them from different angles so you can start

[00:26]

recognizing them for yourself. A quick note, this is educational. For diagnosis or medication,

[00:33]

please keep working with your doctor. Now take a deep breath and let's dive in.

[00:38]

In this episode, you will learn why your brain can continue looking for danger long after you've

[00:44]

left a difficult relationship, and why knowing you're safe doesn't always mean feeling safe.

[00:50]

How prolonged emotional stress may affect your sleep, your sensitivity to pain,

[00:54]

and your migraine patterns, even when life has finally become calmer. And why imagining danger

[01:01]

can create real physical reactions in your body, and how understanding this connection can change

[01:06]

the way you interpret your symptoms. Stay with me till the end because you will discover why

[01:12]

leaving a stressful relationship and feeling safe again are not necessarily the same event,

[01:17]

and why understanding this difference matters for your migraine. Now imagine this, you have

[01:24]

finally left a relationship that was exhausting. Perhaps your partner was unpredictable, and one day

[01:32]

everything was wonderful. The next, you were walking on eggshells, and perhaps there were

[01:37]

constant arguments, silent treatments, or criticism that seemed to come out of nowhere. Perhaps you

[01:44]

never quite knew which version of that person you were going to meet when you came home. And slowly,

[01:50]

without even realizing it, you became very good at noticing the smallest details. The sound of

[01:55]

footsteps, the way a door closed, a change in someone's tone of voice, a message that was shorter than

[02:02]

usual. And these details mattered because they helped you anticipate whether the evening would

[02:07]

be peaceful or difficult. And then one day, you leave. The argument stops, the messages become

[02:15]

less frequent, your home becomes quiet, and finally you should feel relieved. Perhaps part of you does,

[02:24]

but something strange happens. You still wake up at three in the morning, your heart still races

[02:29]

when your phone rings, you find yourself studying people's facial expressions and wondering whether

[02:34]

they're upset, your shoulders remain tense even when you're sitting comfortably on your sofa,

[02:40]

and the migraine attacks? Perhaps they haven't disappeared. Perhaps they're even happening more

[02:47]

often. And you start wondering, why am I still feeling like this when the stressful situation

[02:52]

is finally over? Well, there's something fascinating about how our brain works. Your brain doesn't

[02:58]

simply react to what's happening around you, it also uses past experiences to predict what

[03:03]

might happen next. And when you've spent months or years in an environment where you feel threatened,

[03:10]

your brain may have become particularly good at predicting danger. The difficulty is that the brain

[03:15]

doesn't necessarily stop making those predictions just because your situation has changed.

[03:20]

Now, scientists have a word for this heightened state of alertness, and it's called hypervigilance.

[03:26]

So it simply means being unusually attentive to possible threats, even when there may be

[03:32]

no immediate danger. So let me give you an image. Imagine your brain has a security guard,

[03:38]

and in a relatively safe environment, that security guard can sit comfortably, occasionally

[03:43]

check the cameras, and respond when something genuinely needs attention. But imagine that the

[03:48]

building has experienced repeated break-ins. Suddenly, the security guard cannot afford to

[03:54]

relax. Every sound becomes important, every moment needs to be checked, every unexpected event might

[04:00]

signal trouble. Now imagine that this continues for months or even years, and the security guard

[04:06]

becomes extremely good at detecting possible danger. And then, one day, the building becomes

[04:12]

safe again. The locks are changed, the threats are gone, but the security guard is still standing,

[04:18]

still watching, still expecting something to happen. The environment has changed, but the

[04:22]

security system hasn't yet adjusted. Something similar can happen in the human brain after

[04:27]

prolonged emotional stress. Different brain networks help us reorganize threats, remember

[04:33]

past experiences, and decide how to respond. The amylda, for example, plays an important role in

[04:38]

identifying emotionally significant information, including potential danger. And the hippocampus

[04:43]

helps us connect experiences with memories and context. And part of the prefrontal cortex helps

[04:49]

us evaluate situations and regulate our responses. These systems work together continuously. But when

[04:55]

someone has experienced repeated emotional threats, reminders of past experiences may continue

[05:00]

triggering strong reactions, even when the original situation has ended. Of course, it doesn't

[05:06]

happen to everyone, and hypervigilance doesn't automatically mean someone has a trauma-related

[05:11]

disorder. But it helps explain something that can otherwise feel very confusing. You can intellectually

[05:18]

know that you're safe, while your brain continues behaving as though danger might be just around the

[05:24]

corner. You can intellectually know that you're safe, while your brain is going to continue to

[05:29]

behave such as though danger might just be around the corner. And this is why telling someone just

[05:35]

relax is rarely enough. Because relaxation isn't simply a decision. Your brain may need time and

[05:43]

new experiences to adjust what it has learned to expect. And for someone living with migraine, this

[05:48]

is particularly relevant. You know, because we know that migraine is simply not caused by stress.

[05:54]

It's more complex. And it's complex in ways that involve changes in how the brain processes sensory

[06:00]

information and pain. But that neurological system, it doesn't operate in isolation. It interacts with

[06:05]

your sleep, with your daily rhythms, with your emotional state and your body's response to stress.

[06:10]

And this is where an interesting scientific concept comes in. In 2012, an article published

[06:14]

in the journal Neuron explores a migraine through the concept of allostatic load. Now that's a

[06:19]

complicated expression for something quite intuitive. Your body is constantly adapting to

[06:24]

the demands of life. And when you face a stressful situation, it adjusts. Your heart may beat faster,

[06:30]

your muscles may become more tense, your attention sharpens, your sleep becomes lighter. And all of

[06:35]

these changes can be useful when you're dealing with a challenge. But what happens when the

[06:41]

challenges never seem to stop? When you're not dealing with one difficult conversation, but years

[06:47]

of unpredictability. When your body is repeatedly preparing for something unpleasant. And scientists

[06:52]

use the term allostatic load to describe the cumulative burden that can develop when the

[06:58]

body's regulatory system are repeatedly called upon to adapt. Now the article in Neuron proposed

[07:04]

that migraine may be understood in part through disturbances in these adaptive processes. This is

[07:10]

a scientific model, not a proof that emotional trauma causes migraine. But it gives us another

[07:15]

way to think about the relationship between chronic stress and neurological vulnerability.

[07:20]

Imagine someone who spent years in a difficult relationship. They may sleep poorly, they may

[07:25]

skip meals because they're anxious, they may constantly monitor their partner's mood, their

[07:30]

entire day may be organized around anticipating problems, and then they leave. But their sleep

[07:35]

doesn't immediately improve, their muscles don't necessarily relax, their attention doesn't suddenly

[07:40]

drop searching for threats. The relationship has ended. Some of the patterns associated with living

[07:47]

in that relationship may remain. And for a person who already has migraine, these continuing

[07:53]

disturbances, they may matter. Not because their migraine is imaginary, not because they're too

[07:58]

emotional, but because stress regulation, sleep, and pain processing are interconnected. Now

[08:03]

interestingly, researchers also found associations between interpersonal violence and migraine.

[08:09]

There was a study in 2011, a study published in Headache, the journal of head and face pain,

[08:16]

that examined more than 2,000 women in Peru, so in Latin America. And researchers found that

[08:22]

women who reported physical or sexual violence from an intimate partner had higher odds of migraine

[08:29]

than women who did not report those experiences. Now this is an observational study, but it does

[08:35]

suggest something important. When we're trying to understand someone's migraine history, their

[08:40]

experiences of interpersonal threat may be relevant to the bigger picture. And that brings us to another

[08:46]

fascinating question. What happens when the threat is no longer physically present, but the brain

[08:52]

continues anticipating it? Now let's approach this from a different angle. Traditional transvestite

[08:59]

has long emphasized the relationship between our emotional experiences and our physical state. And

[09:06]

while its traditional explanations may differ from modern science, I find the idea, the underlying

[09:11]

idea, particularly interesting. It's the mind and the body are not two completely separate worlds.

[09:15]

What happens in one can influence the other. Or if you want to say in short, what's in your head

[09:21]

actually is in your body. And the West is catching up on that. So sometimes the West looks very

[09:25]

polished and very scientific, which is true, but it's also catching up on these old concepts that

[09:30]

we come back to. Now imagine something really simple. And I'd like you to do that. Okay. So

[09:35]

you're listening to the podcast and you're going to do something for me. I'm going to have you

[09:39]

imagine biting into a fresh lemon. You can see the lemon and now we're going to cut it in two.

[09:46]

And I'm going to put it on your lips and squeeze it a little bit. And you have a bit of lemon.

[09:51]

Now you bite into it and a sharp acidic juice spreads across your tongue. Can you almost taste

[09:58]

it? Perhaps you even notice your mouth beginning to produce saliva. Did you notice that? It worked

[10:03]

for me. But here's the interesting part. There is no lemon and you haven't eaten anything. You

[10:08]

simply imagined it and yet your body may be responding. Now let's try a different example.

[10:15]

Imagine hearing a door slam. Not just any door. The door you used to hear when someone got angry

[10:24]

at you. That door slam. Perhaps you remember the footsteps or the silence before an argument or

[10:30]

that uncomfortable feeling of needing to be careful about what you said next. And just by remembering

[10:35]

the situation, you might notice something changing. Your shoulders become tense and your breathing

[10:40]

becomes shallower and your stomach tightens. But look around. Nobody entered the room. The danger

[10:46]

is not happening now and yet your body may be responding as though it needs to prepare for it.

[10:52]

Something that exists only in your memory or in your imagination can sometimes produce a very real

[11:00]

physical reaction. Now it does not mean that imagining danger makes danger happen. And it

[11:05]

certainly doesn't mean that you're creating your own migraine. But it shows us something

[11:10]

fundamental about the connection between the mind and the body. The body can influence the mind.

[11:15]

But the mind can also influence the body. And this brings us back to a perspective that has

[11:20]

been explored for centuries in traditional Chinese medicine. So the fact that the mind and body are

[11:24]

deeply interconnected and that emotions are not viewed as experiences that happen exclusively

[11:29]

in our thoughts. They're also interpreted through their relationship with movement of something

[11:34]

called Qi, which often translates as vital energy. Now within this traditional framework, fear is

[11:40]

associated with a downward movement of Qi. Worry and repetitive thinking are associated with Qi

[11:47]

becoming constrained or knotted. That is what makes you want to go pee, that downward movement

[11:52]

of Qi. And when emotional experiences remain unresolved, practitioners may describe patterns

[11:58]

of tension or stagnation. What occupies our mind can influence what we experience in our body.

[12:07]

I'll just repeat it because it's so useful for so many aspects of life. What occupies our mind can

[12:13]

influence what we experience in our body. Interestingly, modern neuroscience provides

[12:19]

a parallel observation. Research has showed that imagining threatening situations can produce

[12:25]

measurable physiological responses. Your heart may beat faster, your attention may be more focused

[12:31]

on physical danger, your body may prepare for something that isn't actually happening in the

[12:35]

present moment. And the traditional and scientific explanations are not the same,

[12:39]

but both invite us to pay attention to the connection between emotional experience and

[12:43]

physical responses. And the traditional and scientific explanations both invite us to pay

[12:48]

attention to the connection between emotional experience and physical response. Now imagine

[12:52]

someone who's spent years anticipating emotional danger. They have finally left, they may have moved

[12:59]

to a new home, they may have changed their routines and perhaps even rebuilt an entire life. But

[13:03]

mentally, they may still be having the old conversations, still anticipating criticism,

[13:08]

still wondering what could go wrong, still preparing to defend themselves. And when these

[13:12]

memories or expectations appear, their body may react. Not because they're choosing to remain

[13:18]

afraid, but because their brain has learned to associate certain situations with danger. And for

[13:23]

someone living with migraine, these reactions may become part of a wider pattern involving stress,

[13:28]

poor sleep and altered pain sensitivity. Again, this doesn't mean your thoughts are causing your

[13:33]

migraine, and it doesn't mean that you can think your pain away, but it does remind us that the

[13:40]

relationship between the mind and the body works in both directions. Physical pain can change how

[13:44]

we think and feel, and our thoughts and emotions can influence our physical experience. Now there's

[13:50]

a simple image I want you to remember. Imagine carrying a very heavy bag. At first you can manage

[13:55]

it, but after a while your arm becomes tired, and your shoulder begins to ache, and your muscles are

[14:01]

constantly working to support the weight. Now imagine after a couple of hours you can put the

[14:06]

bag finally down and the weight is gone, but your arm doesn't immediately feel normal again. Your

[14:13]

muscles may still ache, you may have tingling sensations in pins and needles, and you need time

[14:19]

to recover. And I think that is a beautiful way to understand what can happen after leaving a

[14:24]

difficult relationship. The removal of a burden and the recovery from carrying it are not the same

[14:30]

thing. You may have removed the sources of the stress, but your mind may still be anticipating it,

[14:36]

your body may still be reacting to familiar reminders, and your daily routines may still

[14:40]

reflect years of trying to avoid conflict. In traditional Chinese medicine, practitioners

[14:44]

describe the process of recovery as restoring movement where there has been constraint,

[14:49]

and balance where there has been strain. So from a modern perspective, we might think about

[14:54]

gradually changing learned expectations and recovering more flexible responses to stress.

[14:59]

These are different frameworks, but they bring us toward the same practical question.

[15:04]

How do you begin building a life where your body no longer needs to prepare for the same threats

[15:10]

every day? Because sometimes the person is gone, the arguments are gone, the danger are gone,

[15:16]

but the expectation of the danger remains. And this is perhaps one of the most important things

[15:20]

to understand about recovery. Leaving is an event. Feeling safe again is a process.

[15:28]

And if there's one thing I want you to take away from today's episode, it is that you can

[15:32]

leave a difficult relationship and still carry some of that pattern into your new life. That

[15:37]

doesn't mean your past is destined to control your future. It means that adjusting to a different

[15:42]

reality may take time. Perhaps you've become so accustomed to anticipating other people's reaction

[15:48]

that you now do it everywhere. At work, with your friends, with your children, even with strangers.

[15:53]

And perhaps you apologize when you haven't done anything wrong. Perhaps you find it difficult

[15:58]

to disagree with someone. And perhaps silence makes you so uncomfortable. Because in the past,

[16:03]

silence meant that something bad was about to happen. And perhaps your migraine patterns have

[16:07]

become more difficult during this time. I want you to approach all of this with curiosity rather

[16:12]

than judgment. Because the objective isn't to blame your past for every symptom. It is to recognize

[16:18]

whether there are patterns that deserve your attention. And perhaps one useful place to begin

[16:23]

is by asking yourself a simple question when you notice that familiar tension. Am I responding to

[16:28]

something happening right now? Or to something my brain has learned to expect? The danger may be over.

[16:35]

But the process of feeling safe may only just be beginning. And if you enjoyed this podcast and

[16:42]

made you feel good, just listen to it again. That's okay. Just to have these thoughts cherished in your

[16:49]

heart. Peace is coming your way. That's all for today. I hope this episode helped you notice

[16:56]

some new things. If you'd like to keep exploring your patterns, you can find us on

[17:01]

MigraineHeroes.com. Your body has a story to tell. Let's keep listening. I will be back with you soon.

Originally published November 2026

References

Understanding Migraine Through the Lens of Maladaptive Stress Responses: A Model Disease of Allostatic Load (Borsook et al., 2012): This review explores how repeated stress and allostatic load may contribute to migraine biology. Read more <u>here</u>.

Association Between Intimate Partner Violence, Migraine and Probable Migraine (Cripe et al., 2011): This study found an association between intimate partner violence and migraine among women, without establishing causation. Read more <u>here</u>. 

Traumatic Life Experience and Pain Sensitization: Meta-Analysis of Laboratory Findings (Nanavaty et al., 2023): This meta-analysis found a small association between psychological trauma and increased laboratory pain sensitivity. Read more <u>here</u>.

Don’t miss an episode

Subscribe to the Migraine Heroes Podcast on your favorite platform and get evidence-based insights twice a week.

Back to Migraine Science

Curious about the Migraine Heroes approach?

Discover your unique Migraine Profile—a clear picture of why recovery has been difficult. This report will shed light on the complexity of your migraines and reveal your healing potential.

Take Your Free Migraine Assessment

More about Emotions