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Why Anticipatory Anxiety Triggers More Migraines and How to Stop It
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Why Anticipatory Anxiety Triggers More Migraines and How to Stop It

10 min

Do you fear the next migraine before it hits? Learn how anticipatory anxiety triggers pain and how to break the cycle for good.

00:00
-10:00

What if the fear of your next migraine is the very thing keeping it alive?

In this episode of Migraine Heroes Podcast, host Diane Ducarme dives deep into the fear–migraine feedback loop**, ** how the mere anticipation of pain can activate the same pathways as pain itself. We explore how chronic fear trains your brain to stay on high alert and how that hypervigilance quietly keeps your nervous system in “migraine mode.”

You’ll discover: 💭 How the fear of the next attack can actually spark the next attack, and the science behind that feedback loop. 💭 Practical ways to interrupt the anticipation spiral so you can regain calm, control, and confidence. 💭 Why blending Eastern-medicine wisdom (the art of releasing fear through flow) with Western neuroscience (the science of neuroplasticity and safety signals) creates a whole-new way out. This episode is for anyone who’s ever woken up scanning for warning signs — or felt their heart race at the first twinge of pain. You’ll learn how to stop living for your migraines and start living beyond them.

🎧 New episodes every Monday and Wednesday 🔗 Discover our work on migraineheroes.com

References: The Not So Hidden Impact of Interictal Burden in Migraine: A 2022 narrative review in Frontiers in Neurology (Vincent et al.) shows that migraine has significant effects even between attacks—such as sensitivity, mood changes and balance issues—highlighting the continuous burden of the condition. Read the full review here. Altered Neural Activity to Monetary Reward/Loss Processing in Episodic Migraine: A 2019 study in Scientific Reports (Kocsel et al.) found that individuals with episodic migraine have decreased neural reactivity in the brain’s reward system when processing monetary rewards, suggesting altered neural processing beyond pain episodes. Read more here. Are Some Patient-Perceived Migraine Triggers Simply Early Manifestations of the Attack?: A 2021 review in PMC discusses how symptoms patients interpret as triggers—such as food, stress or weather—may actually be early-phase migraine indicators, shifting our understanding of “trigger” versus prelude. Read the full article here. Premonitory Symptoms in Migraine: An earlier seminal study in Neurology (2003) investigated premonitory symptoms—such as mood changes, yawning and cravings—showing how the brain shifts state before the headache phase, thus reframing migraine as a multi-phase brain event. Read the study here.

Disclaimer: This podcast is for informational purposes only and does not substitute for providing medical advice. Always consult your healthcare professional before making any health-related decisions. For women, men, and children who suffer from migraine disease, Migraine Heroes is your go-to resource for understanding, managing, and overcoming migraine attacks. We cover all types of migraines and related headaches, including primary and secondary migraines, chronic migraines, and cluster migraines. We dive deep into the complexities of migraine with aura and migraine without aura, as well as rarer forms like hemiplegic migraine, retinal migraine, and acephalgic migraine (silent migraine). Our discussions also extend to cervicogenic headaches, ice pick headaches, and pressure headaches, which often mimic migraine or contribute to overall migraine burden.

Transcript

[00:00]

What if the moments before your migraine are actually fueling the next one?

[00:05]

In this episode, we unpack how anticipation is reality.

[00:12]

Migraine Heroes is a podcast for chronic migraine sufferers who've seen countless doctors with no

[00:18]

results. Learn how to reduce your migraine attacks without endless medications or constant sacrifices.

[00:26]

Hello, I'm Diane Ducarme. I've helped over 500 people break free from migraine,

[00:32]

even after suffering for up to 60 years. My mission in life? To bring this relief

[00:37]

to a million people using a unique blend of Eastern medicine and Western science.

[00:46]

In this episode, you will learn how your fear of the next attack can actually trigger the next

[00:51]

attack. Practical strategies to interrupt the anticipation loop so you can regain control over

[00:57]

your body and of your migraine cycle. And why combining an Eastern medicine mindset

[01:04]

with Western neuroscience gives you a whole new pathway out of the fear spiral and into freedom.

[01:11]

Stay with me till the end because understanding what's happening in your brain gives you power

[01:16]

to change it. Migraine is far more than occasional head pain. Between attacks, you may still be

[01:24]

living in a state of alert, of waiting, of expectation, what we call the fear spiral.

[01:32]

Research is showing that this anticipatory state isn't harmless. It influences the next attack,

[01:39]

the inner attack burden, and keeps you locked in a cycle. For example, a recent overview shows

[01:46]

that the inter-rectal phase, so the time between migraine attacks, carries substantial burden,

[01:53]

hypersensitivity, cognitive and emotional load, anxiety about the next attack.

[02:00]

Now, an interesting study came out in 2021 by Karazhan and her team, and they asked an important

[02:08]

question, are some of the things we call triggers actually early warning signs from the brain

[02:14]

itself? In other words, maybe it's not that coffee, stress, or certain foods cause the migraine,

[02:22]

but that your brain is already shifting in migraine mode and you're simply noticing those

[02:27]

signals. So okay, here I'm not sure I like it because it's also accusing someone of self-triggering

[02:34]

the migraine, and I think we need to be very careful with that language. That being said,

[02:40]

when I reflect on this, the gut-brain axis is bi-directional, meaning that your brain

[02:44]

communicates with your gut and your gut communicates back here with your brain.

[02:47]

And in the Eastern world, there's also an emotion-to-gut axis. Emotions will influence

[02:53]

your gut and your brain, and vice versa. And in the West, we have seen this notion in the

[02:58]

vagus nerve being damaged on children who have been abused. So in the West, we also know that

[03:03]

emotions play a critical role when it comes to health. And so how you perceive a trigger can

[03:10]

technically influence your experience. And when I was reading this initially, I was a bit against

[03:16]

it or I didn't like the way it was formulated. But when I reflect on it, I'm also reflecting

[03:21]

on our app and I'm genuinely reflecting on our app as I'm preparing for this podcast. And

[03:26]

while we let people know of fast and slow triggers inside the app, we never put emphasis on them.

[03:34]

And I think there's two reasons for that. Number one is they will go away. So over time,

[03:39]

a trigger shouldn't be a trigger. It's a reflection of an imbalance inside of the body.

[03:44]

And so there's no need, number two, to obsess with those unless, and there's an unless,

[03:51]

they are part of your day to day. And so I find that from my perspective, the way I find it most

[03:57]

useful, this part of the app, that it's an aha moment of sometimes someone saying, oh, I take

[04:03]

this food every day or I have that habit every day. It can be protein powder that they take every

[04:07]

day. It can be a flat white, a cafe latte that they take every day. It can be kombucha that they

[04:13]

take every day, a liter that they brew. And all of these will cause the migraine. So from that

[04:17]

perspective, it's interesting, but it's not interesting from the moment it becomes an

[04:22]

obsession because it should go away. And so when you look at the food podcast, they will teach you

[04:27]

things that are important to avoid in your day to day and having them occasionally is not harmful.

[04:32]

And so of course, even more interesting, they found that the fear or avoidance of those sensations

[04:37]

like tension, cravings, or fatigue might actually amplify the process, making the nervous system

[04:43]

even more reacting. And yet another study by Griffin et al found that 72% of migraine

[04:49]

attacks were preceded by premonitory symptoms like fatigue, difficulty concentrating,

[04:54]

which could all be interpreted as early warning signs of the brain heading into an attack mode.

[05:00]

And so the hypothesis on how anticipation keeps the migraine alive is that when you begin expecting

[05:07]

a migraine, you shift into a hypervigilant state. Your nervous system is primed for threat.

[05:13]

You know, it's coming. And that means heightened sensory sensitivity, increased the stress hormones,

[05:19]

cortical excitability. And look, I'm saying this with a lot of gold in my voice. Like this is

[05:26]

awful. I mean, absolutely awful. Especially if you know that the migraine is going to hit

[05:31]

every single day at a specific time of the day is just unbearable, absolutely unbearable. So

[05:36]

bear with me. I'm trying to just explain and give you a few tools that may help you observe

[05:43]

yourself in those moments of fear. The second hypothesis on how that anticipation keeps the

[05:49]

migraine alive is that the brain may misinterpret some of the early signs like mild sensory changes,

[05:56]

ache behind the eyes, mood changes as full-blown impending attack. So your emotional system is

[06:02]

going to react. The anxiety increases and you may withdraw. You may avoid activities and this

[06:07]

avoidance and anxiety heighten the nervous system activation and may lower your threshold for the

[06:13]

next attack. So over time, that's going to create a kind of feedback loop, attack,

[06:18]

relief, anticipation, hyper-vigilance, stress system attack. And that's a fear spiral.

[06:23]

And that's a spiral that we try to break literally. In the new version of the app,

[06:28]

we're releasing an emotion management section to just really help you get out of that loop

[06:34]

because then the foods can do their job and we can undo some of the underlying imbalances.

[06:40]

And so this means that you do not just want to treat the attack when it comes,

[06:45]

you want to intervene earlier in this anticipatory phase before full activation happens.

[06:52]

Recognizing that the waiting itself is active and that your body is doing work in those

[06:57]

anticipatory hours, days, opens a new frontier for relief. So you'll want to monitor, you just

[07:03]

want to observe, how do you feel when you anticipate a migraine? What are your habits

[07:08]

of avoidance and hyper-vigilance? What are the emotional states that is in between these times?

[07:15]

Because these are not passive, they're just really part of the cycle. And by doing this,

[07:19]

you can start to break the loop. Now, this is another interesting study I came across as I

[07:24]

was doing this research. And it's a study that looks at how the brain of some with migraine

[07:30]

responds to rewards and losses. And they found that when people with migraine expected a reward,

[07:36]

say something good was about to happen, their brains lit up just like everyone else.

[07:42]

But when they actually received the reward, that final moment of satisfaction,

[07:46]

a specific part of the brain called the right inferior frontal gyrus, didn't activate as

[07:52]

strongly. In other words, the anticipation of pleasure was there, but the follow-through,

[07:57]

that ability to fully feel and enjoy the reward, seemed muted. And I find it a fascinating glimpse

[08:05]

into how migraines isn't just about the pain, can suddenly shape how your brain experiences joy,

[08:12]

motivation, and relief. Such as if the joy itself was listened. And I find it interesting because

[08:19]

when we work with people, and that over time they have fewer migraines, they say that they

[08:25]

actually started seeing their life more in colors. And that's exactly what people describe. And that's

[08:29]

why the app and the logo are a little bit more bright in colors. And we thought, how bright can

[08:34]

we go? And I think with the years, we'll go brighter. We're still quite muted, but we go

[08:38]

brighter because that's what we want back for you in your life. I genuinely mean it. I personally

[08:45]

find it's quite fascinating because it's like this too can be reversed. And so for you, for today,

[08:51]

what I'd like you to take out from this podcast is when you know the pain is going to come,

[08:57]

because this is the time of the pain, just accept it. Don't fight it. Try to accept it like a naughty

[09:04]

friend that is coming to visit and try to make you experience the pain in a safe way. Take something

[09:11]

that makes you feel safe. Just observe the pain and don't attach too much emotion to it. Just let

[09:18]

it go. Let it pass and hold on to what makes you feel safe. And we've seen that when you start

[09:25]

to do that, you can start to gently break that cycle. More on this in other podcasts. And remember,

[09:33]

every small step you take moves you closer to freedom. You are powerful, you are resilient,

[09:40]

and you are no longer alone. Keep rising. My Green Hero.

Originally published December 2025

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