Migraine Heroes
Resentment, Stress & Migraines: Releasing What Your Body Still Holds
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Resentment, Stress & Migraines: Releasing What Your Body Still Holds

11 min

Does resentment linger in your body? Discover how holding on fuels stress chemistry, and how release can ease migraine pain.

00:00
-11:00

Some memories don’t fade, they echo. A word, a glance, a moment that keeps the body on alert long after it’s passed. Your brain remembers the pain, and your chemistry follows.

In this episode of Migraine Heroes Podcast, host Diane Ducarme explores how holding on to anger, guilt, or resentment, keeps your nervous system locked in defense mode. Neuroscience shows that unforgiveness isn’t just emotional; it’s chemical. And Eastern philosophy has been teaching this for thousands of years: peace is not a mood,  it’s a biological state.

You’ll discover: 💡 How resentment and rumination keep your stress chemistry “on,” flooding the brain with cortisol and adrenaline 💡 The key brain regions — like the amygdala and prefrontal cortex — that shift when you practice forgiveness 💡 How forgiveness lowers inflammatory markers, improves heart rate variability, and helps regulate chronic pain and migraine sensitivity 💡 What Eastern wisdom traditions reveal about releasing emotional stagnation — and why true forgiveness restores inner flow

You’ll also learn simple, science-backed ways to help your brain and body let go — not by forcing it, but by re-training your chemistry toward calm.

If you’ve ever felt trapped by your own thoughts, or noticed how emotional stress triggers physical pain, this episode is for you. Tune in to learn how forgiving others — and yourself — can become one of the most powerful medicines for your brain.

🎧 New episodes every Monday and Wednesday 🔗 Discover our work on migraineheroes.com

References:

  • Forgiveness and Reconciliation: Theory and Application — Routledge (2016): Worthington E.L. and Hook J.N. presented a comprehensive framework showing how forgiveness interventions strengthen emotional regulation, empathy, and relational repair, with implications for trauma and chronic pain recovery. Explore the book here.
  • Forgiveness, Stress & Health (2016): Toussaint et al. show that practicing forgiveness reduces stress reactivity over just five weeks, supporting its role in lowering inflammation and improving emotional well-being. Read more here.
  • Alterations in Brain and Immune Function Produced by Mindfulness Meditation — Psychosomatic Medicine (2003): Davidson R.J. and Kabat-Zinn J. demonstrated that eight weeks of mindfulness meditation increased left-frontal activation (linked to positive emotion) and enhanced immune response, highlighting forgiveness’s neurological parallels. Read the study here.
  • **Forgiveness, Physiological Reactivity and Health: The Role of Anger — Radboud University Nijmegen (2008): **Witvliet, C. shows how unresolved anger heightens physiological stress responses—elevating heart rate, cortisol and autonomic arousal—while forgiveness promotes healthier emotional regulation and improved physical wellbeing. Read the full text here.

Disclaimer: This podcast is for informational purposes only and does not substitute for providing medical advice. Always consult your healthcare professional before making any health-related decisions. For women, men, and children who suffer from migraine disease, Migraine Heroes is your go-to resource for understanding, managing, and overcoming migraine attacks. We cover all types of migraines and related headaches, including primary and secondary migraines, chronic migraines, and cluster migraines. We dive deep into the complexities of migraine with aura and migraine without aura, as well as rarer forms like hemiplegic migraine, retinal migraine, and acephalgic migraine (silent migraine). Our discussions also extend to cervicogenic headaches, ice pick headaches, and pressure headaches, which often mimic migraine or contribute to overall migraine burden.

Transcript

[00:00]

You replay the scene in your head, what was said, what wasn't, what still hurts, your

[00:06]

joint tenses, your chest tightens, your heart races.

[00:10]

Resentment isn't just emotional, it's biochemical.

[00:17]

Migraine Heroes is a podcast for chronic migraine sufferers who've seen countless

[00:22]

doctors with no results.

[00:25]

Learn how to reduce your migraine attacks without endless medications or constant sacrifices.

[00:31]

Hello, I'm Diane Ducarme, I've helped over 500 people break free from migraine, even

[00:37]

after suffering for up to 60 years.

[00:40]

My mission in life?

[00:42]

To bring this relief to a million people using a unique blend of eastern medicine and western

[00:47]

science.

[00:51]

In this episode, you will learn how resentment and rumination keep your stress chemistry

[00:56]

locked on, what brain regions and hormones shift when you practice forgiveness, and how

[01:02]

both western neuroscience and eastern philosophy teach the same truth, peace is physiology.

[01:09]

Stay with me till the end, because once you see what resentment does inside the brain,

[01:15]

forgiveness stops being abstract and becomes deeply practical.

[01:19]

And by the end of this episode, you will know what makes me angry on a day-to-day basis.

[01:25]

When you relive a painful event, your brain doesn't label its memory, it experiences

[01:30]

it again in real time.

[01:33]

The amylda, the brain's emotional alarm, fires, and the hypothalamus sends signal through

[01:39]

the HPA axis, releasing cortisol and adrenaline.

[01:43]

Your heart rate rises, your blood pressure spikes, inflammation increases, and if you

[01:49]

repeat that pattern daily, through resentment, anger, and silent rumination, those hormones

[01:55]

stop being acute responses, they become your baseline.

[02:00]

Chronic activation of this loop has been linked to fatigue, anxiety, cardiovascular disease,

[02:05]

and migraine.

[02:06]

A 2019 study in Frontiers in Psychology found that people who habitually replay grievance

[02:12]

show increased activity in the posterior cingulate cortex, a region tied to self-referential

[02:18]

thought and stress persistence.

[02:21]

By contrast, subjects trained in forgiveness practices showed greater activation in the

[02:27]

ventromedial prefrontal cortex, the brain's self-soothing and empathy center.

[02:32]

Forgiveness then is not moral permission, it's a neurological release.

[02:38]

Forgiveness interrupts the cortisol feedback loop and restores parasympathetic tone, your

[02:43]

body's rest and repair mode.

[02:45]

Another meta-analysis from Annals of Behavioral Medicine in 2021 found measurable drops in

[02:51]

inflammatory markers after consistent forgiveness exercises, especially IL-6, a key cytokine

[02:57]

linked to chronic pain and depression.

[03:00]

Forgiveness isn't letting someone off the hook, it's taking your nervous system off

[03:04]

theirs.

[03:05]

So, I want to share this story about a man, it's a very, very private story, so I'll

[03:10]

keep the details immensely generic as to no name and no location.

[03:15]

So it's a man, he lives in the US, he is an executive in a company.

[03:19]

We worked together, this was three, four years ago, and his migraines drastically improved.

[03:24]

He was really down to a very low grades, regular, but very, very low type of migraine, he could

[03:29]

completely concentrate at work, until one day, a little bit out of the blue, he had stopped

[03:34]

tracking.

[03:35]

He sends me a very strong message on WhatsApp and says, it doesn't work, I have migraines

[03:41]

again, and I'm infuriated, and I said, oh, I replied immediately, I said, I felt so bad,

[03:46]

I was like, I'm so sorry that, I don't know, like your patterns seem to be so good,

[03:51]

I'm so sorry for what's happening, let me help you out.

[03:54]

And so I continued to text him, at the time I did not have the Migraine Heroes app yet,

[03:58]

so this was all on WhatsApp.

[04:00]

I text him and I say, well, is there any context, is there anything that changed while I go

[04:05]

in your profile and in your data?

[04:07]

And he replied to me, something I did not expect, he replied to me, my father died.

[04:13]

And I said to him, oh, okay, very sorry for that, can you send me a picture of your tongue?

[04:17]

Now, the tongue, if you know my work, it's really related to a muscle that relates to

[04:22]

your base nerve and is an amazing map into your gut brain axis, incredible.

[04:27]

You know, you can see on our app, we always ask for a picture of your tongue.

[04:31]

And so on his tongue, which I asked 24 hours later, I write to him and I say, look, I'm

[04:35]

so sorry to be a bit off boundary here, but I'm not seeing grief on your tongue, I'm seeing

[04:40]

anger and resentment, can that be?

[04:43]

And then he replied to me, he said, oh gosh, you know, I've done years of therapy, I am

[04:47]

deeply angry at my father for a lot of reasons, I just, please, I just, I just don't want

[04:53]

to talk about it.

[04:54]

And I said to him, look, it's absolutely okay, I can either ask you to forgive to your father

[04:59]

or to stop being angry at him, which is really difficult in the case because he's no longer

[05:04]

there anyway, and he's leaving his mess behind,

[05:07]

or I can ask you to have a chamomile and goji berries infusion or a chamomile infusion.

[05:11]

So, you know, there you go.

[05:13]

And just in a couple of days, he was back to his norm because the more he was going

[05:16]

to be angry, the more he was going to have migraines, but the more he was having migraines,

[05:20]

the more it would flare up his liver.

[05:22]

You see the emotional to gut axis is bidirectional.

[05:26]

And so within three days, we got him back on track.

[05:28]

And I just want to illustrate this example of how the anger and how the resentment really

[05:36]

acts like a boomerang, like you think you're harming the person in front, but really the

[05:41]

first person that you're harming is yourself.

[05:44]

And I'll share my own story later.

[05:46]

In traditional Chinese medicine and Buddhist psychology, like resentment is seen as heat

[05:51]

of the heart, what we call heart fire can be also live a fire.

[05:56]

And when anger or injustice isn't expressed or resolved, it becomes an internal fire burning

[06:03]

the chest, tightening the breath and disturbing the sleep.

[06:07]

But fire in the sense isn't evil. It's energy without direction.

[06:12]

And when you hold a grudge, that energy circles inward.

[06:16]

And when you forgive, it moves outward, transforming into compassion, which naturally cools the

[06:20]

system.

[06:21]

Eastern teachings don't define forgiveness as approval.

[06:26]

They define it as release of resistance, not saying it's okay, but saying, I will no

[06:31]

longer carry this.

[06:34]

Breathing into the chest, exhaling longer than you inhale, literally signals the vagus

[06:38]

nerve to relax, placing a hand on the sternum while exhaling releases the tension that resentment

[06:45]

hides inside.

[06:47]

And over time, these small rituals retrain your emotional circuitry to recognize peace,

[06:54]

not as passivity, but as safety.

[06:57]

And from safety, the mind can finally soften, the fire dims, the body cools.

[07:02]

In both frameworks, neuroscience and Eastern medicine, forgiveness is re-regulation.

[07:08]

That's what happens when the storm stops spinning and the heart remembers its home.

[07:12]

So if you've been holding on to anger, betrayal, disappointment, remember your body is holding

[07:18]

on it too.

[07:20]

Every thought sends a chemical and every memory writes a hormone.

[07:26]

Forgiveness isn't for them. It's for the system you live inside every day.

[07:31]

It's the decision to stop being triggered by the past and starting being present in

[07:36]

your own life again.

[07:38]

You don't have to forget. You just have to stop re-injuring yourself through replay over

[07:43]

and over again.

[07:45]

Because when you release resentment, you don't erase history. And the peace that follows isn't

[07:49]

philosophical, it's physical.

[07:52]

I wanted to share what sometimes, and sometimes in my day to day, makes me not angry, but

[07:58]

frustrated.

[07:59]

So I've been living here in New Zealand for the last 10 years, and I'm incredibly grateful

[08:04]

for it.

[08:05]

I mean, it is just paradise.

[08:07]

It's been a home to my children, it's been a home to my family.

[08:10]

It's allowed us to become a family and spend so much time, quality time together.

[08:16]

It's also allowed me to completely change career 180 degrees.

[08:21]

I discovered what we could do for people suffering from migraines. And from that moment, I never

[08:26]

looked back. And I think New Zealand allowed to reinvent myself and not feel like an imposter

[08:32]

when I was initially one, but own my purpose and own my freedom and move forward.

[08:38]

And since 2019, we've grown and our app has done, you know, amazing things and we're able

[08:45]

soon, very soon, to help people in an automated way.

[08:48]

So give all of our wisdom and our learnings to millions of people worldwide in an automated

[08:55]

way at a small price, which has been for me always, always the end result that I was hoping

[09:00]

for.

[09:01]

And so it's incredible.

[09:02]

And it doesn't come with tremendous hard work.

[09:05]

And so I have a team, there's roughly 12 of us, and all of my team is based everywhere

[09:11]

in the world, mainly concentrated, mainly concentrated in Europe.

[09:15]

And it's difficult for me, I mean, you know, mind you with one in Canada and one, two in

[09:20]

Asia, actually,

[09:21]

it's difficult time zone wise, because it means that every single morning, the day starts

[09:25]

really early and every single evening, the work goes late, which, you know, some funny enough,

[09:30]

I don't mind.

[09:31]

But what I do mind is that in the middle of the day, I have so many things to do, and

[09:34]

I can't access people because they're asleep.

[09:37]

And so that has led me to be sometimes at times resentful, and I have to catch myself

[09:42]

because I can't do that.

[09:44]

So I've, I've learned to have my own techniques to, you know, peace and quiet.

[09:48]

And these days, it's about a good romance and a good love book to just in between really

[09:53]

intense activities, just recenter myself a little bit, or if I'm feeling that way,

[09:58]

to recenter myself.

[09:59]

And so it can be anything.

[10:00]

I think it works wonders.

[10:01]

I know that the universe would take me to a closer time zone to where I need to be.

[10:06]

And meanwhile, I try to focus on the gratitude that I have that this geography allowed to

[10:10]

be on purpose and helping all of you.

[10:13]

And so in your day to day, some things may make you angry, like an unclean kitchen, a

[10:19]

child that forgot his hockey bag and sports bag yet another day, a husband that doesn't

[10:27]

remove his shoes when he comes home, you know, small things like that.

[10:31]

And it's just try to let go, let go of the small things, let go of the larger things

[10:35]

for your own and very selfish importance benefits so you can love and be in return.

[10:41]

And remember, every small step you take moves you closer to freedom.

[10:46]

You are powerful, you are resilient, and you are no longer alone.

[10:52]

Keep rising, my Green Hero.

Originally published December 2025

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Resentment, Stress & Migraines: Releasing | Migraine Heroes