Migraine Heroes
Is Avocado a Hidden Migraine Trigger? What Eastern and Western Medicine Reveal
HormonesGut-BrainGut HealthDietTriggers
Subscribe onBy subscribing to the Migraine Heroes Podcast on Apple or Spotify, you will receive episodes twice a week with fresh evidence-based insights.

Is Avocado a Hidden Migraine Trigger? What Eastern and Western Medicine Reveal

9 min

Could your avocado toast be fueling migraines? Learn why this “health food” may quietly spark pain and inflammation.

00:00
-09:00

That creamy avocado on your toast might not be as harmless as it looks — especially if you’re migraine-prone.

In this episode of the Migraine Heroes Podcast, we dig into a surprising question: Could avocado be making your migraines worse? Diane Ducarme takes you through the journey from traditional Eastern medicine to cutting-edge Western research, revealing how one popular "health food" might be quietly stirring up inflammation and neurological chaos.

You’ll learn: 🥑 Why avocados are considered yin-nourishing in Traditional Chinese Medicine (TCM) — and when that’s a problem 🥑 How avocado acts as a histamine liberator and what that means for your brain and immune system 🥑 The connection between tyramine, digestion, and migraine susceptibility 🥑 Who should avoid avocados — and who might actually benefit from them

Avocados aren’t inherently bad — but if you struggle with a foggy brain, long migraine hangovers, loose stools, or allergies, they may be tipping your system out of balance.

This episode blends real clinical data with 700+ case studies from the Migraine Heroes method. Because no two migraine stories are the same — and healing starts with knowing yours.

🎧 New episodes every Monday and Wednesday

Transcript

[00:00]

Could that creamy avocado on your toast actually be adding to your migraine?

[00:05]

Let's dive into the surprising connection between avocados and migraines.

[00:14]

Migraine Heroes is a podcast for chronic migraine sufferers who've seen countless doctors with no

[00:20]

results. Learn how to reduce your migraine attacks without endless medications or constant sacrifices.

[00:28]

Hello, I'm Diane Ducarme. I've helped over 500 people break free from migraine,

[00:33]

even after suffering for up to 60 years. My mission in life? To bring this relief

[00:39]

to a million people using a unique blend of eastern medicine and western science.

[00:48]

In this episode, you will learn the benefits of avocados from a TCM perspective

[00:52]

and how it can bring your body out of balance as well.

[00:57]

Why avocados may trigger migraines and whether it's you or just the reputation.

[01:04]

And how western studies quantify avocado triggered attacks and what the possible mechanism is.

[01:12]

When I first began this work, I put together a database,

[01:16]

57 functional foods and a handful of herbs, and I thought this would be about it.

[01:22]

Over time, as we were solving more and more complex cases, that number has grown. Today,

[01:28]

we're working with over 750 functional foods, herbs, and their combinations. And one of those

[01:35]

is or was avocado. At a first glance, it seems innocent, beautiful, even. And yes,

[01:42]

it made it quite early into our database. But very quickly, I stopped recommending it.

[01:49]

Despite its reputation, I saw it wasn't restoring balance. In fact, it was doing the opposite.

[01:56]

So today, we'll flip the script. I'll begin with the eastern perspective,

[02:01]

why I initially thought avocado might help. And then we move into the western view to

[02:06]

uncover the nuanced truth about this creamy green fruit. And yes, fruit is exactly what I said,

[02:14]

that was not a slip of the tongue. Avocado is a fruit, more specifically, a berry with a single

[02:21]

large seed. Botanically, it's classified as a fruit because it develops from the ovary of a flower

[02:27]

and contains a seed. And so despite its savory flavor and creamy texture, which often places it

[02:34]

in the vegetable category, in the vegetable category in culinary use, it is technically

[02:40]

a single seeded berry. Now, that's a funny way to look at it. Now, from a traditional Chinese

[02:47]

medicine perspective, avocado is a nourishing and yin-supporting fruit with a rich oily nature that

[02:56]

moistens dryness and replenishes fluids. It enters primarily the lung, the liver,

[03:03]

and the large intestine meridians, helping to lubricate the intestines, soothe the lungs,

[03:09]

and nourish the liver blood. Its soft, creamy texture reflects its ability to calm internal wind

[03:15]

and ease tension in the body. Avocado is especially supportive for individuals with

[03:20]

yin deficiency, dry skin, dry stool, or a tendency toward irritability and restlessness.

[03:26]

Its cooling, slightly sweet and bland nature gently anchors young and moistens without being

[03:33]

overly sweet. So from that perspective, I thought it would be a very attractive fruit,

[03:39]

but people were not responding well to it. So I had to research further and found the following.

[03:46]

So from that perspective, I thought it would be a very attractive fruit, but people were not

[03:51]

responding well to it. I know because at Migraine Heroes, we monitor everyone on their daily

[03:58]

trackers until they reach a stage of no pain. So I had to research further and found the incredible

[04:05]

following. Avocados are rich and oily, yes, nourishing for some, but that same richness

[04:12]

can easily overwhelm a system already struggling with dampness or weak digestion. In traditional

[04:18]

Chinese medicine terms, they're cold and heavy, which means they can slow down the spleen's

[04:23]

transformative function, leading to bloating, fatigue, and even phlegm accumulation. So for

[04:29]

those of us with sluggish digestion, brain fog, or a tendency toward mucus and puffiness,

[04:35]

that creamy green fruit might be doing more harm than good. It's a classic case of something

[04:42]

healthy not being universally balancing. And that was doing part of the explanation,

[04:48]

but that was not fully what I was seeing in people. When I give yin restoring foods, I always

[04:54]

counterbalance them, and it seemed the migraines they were getting were not of that nature. From

[05:00]

the data I could see, it seemed they were acting on migraines in a different way, such as if there

[05:05]

was a flare-up in the liver. But TCM, traditional Chinese medicine, does not report the avocados

[05:12]

being bad on the liver, quite the opposite. So I was really puzzled because what I found in

[05:17]

traditional Chinese medicine was the accuracy was always there, but somehow for that food,

[05:21]

something was missing. So let's turn to the West for a minute. Clinical and observational reports

[05:27]

list avocados to trigger migraines in a subset of patients. Though the overall percentage is

[05:33]

relatively small, it's about 5% in some cohorts, so that's quite small. In the West, avocados are

[05:40]

often flagged as a migraine trigger, however, largely to their tyramine contents, a naturally

[05:46]

occurring amino acid that can influence blood vessels and neurotransmitters linked to migraine

[05:51]

pathways. Tyramine may provoke migraines by causing vasoconstriction or vasodilation

[05:57]

in cerebral vessels, triggering neuronal hyperexcitability in migraine-susceptible

[06:02]

people. And so the tyramine content could explain what I was seeing, but it did not seem to be what

[06:08]

I was seeing. From my data, it did not require too many doses of avocados to trigger more migraine.

[06:15]

And while large-scale randomized trials on avocados specifically are lacking,

[06:21]

elimination diets that remove tyramine-rich foods, including avocados, have shown a reduction in

[06:27]

migraines. So based on our podcast on tyramine and histamine, I went on researching if avocados

[06:34]

were high in histamine, because that would have explained a lot more of what I was seeing.

[06:40]

And from our episode on tyramine and histamine, you now know that a lot of medications such as

[06:45]

the NSAIDs, so think of your Tylenol, your Ibuprofen, your Paracetamol, but also antidepressants,

[06:52]

antibiotics and narcotics, prevent you from breaking down histamine. And I found the gem

[06:58]

I was after for all these years. So here's the twist. Avocados aren't, they're not actually high

[07:07]

in histamine, but they can still cause a reaction. Why? Because they're what we call histamine

[07:14]

liberators, meaning they can trigger your mast cells to release the histamine already stored

[07:22]

in your body. Mast cells are part of your immune system, and when they're easily activated, especially

[07:28]

in people with histamine intolerance or mast cell issues, food like avocado can quietly cause

[07:35]

trouble. Add to that the natural aminazine avocados, which slow down histamine breakdown,

[07:42]

and you've got a perfect storm. So if you're migraine prone or histamine sensitive, that creamy

[07:49]

green fruit might be less of a friend than you thought. So it's not about the histamine they

[07:55]

contain, it's about the histamine they stir up. And that in traditional Chinese medicine is exactly

[08:02]

what it means with dampness. It looks like a liver fire food from a symptoms perspective,

[08:07]

because that heavy release of histamine inside of the body. I always put a lot of thought and

[08:13]

integrity in my podcast. There is so much nonsense out there. I'm trying to show you how your brain

[08:19]

does make sense. And so in many ways today, you taught me something again as I was digging deeper

[08:26]

to provide you better explanations. So now let me cut to the cheese. Who are avocados for?

[08:34]

They are for you if you have a tendency to be constipated, if you have a dry skin. They are

[08:39]

not for you if you have loose stools, if you have phlegm, if you have a foggy brain or long migraine

[08:45]

hangovers, if you have a tendency to have a lot of allergies, if you take medications like

[08:51]

antidepressants or antibiotics or over-the-counter medication for a long time. And remember every

[08:58]

small step you take moves you closer to freedom. You are powerful, you are resilient and you are

[09:05]

no longer alone. Keep rising Migraine Hero.

Originally published July 2025

Don’t miss an episode

Subscribe to the Migraine Heroes Podcast on your favorite platform and get evidence-based insights twice a week.

Back to Migraine Science

Curious about the Migraine Heroes approach?

Discover your unique Migraine Profile—a clear picture of why recovery has been difficult. This report will shed light on the complexity of your migraines and reveal your healing potential.

Take Your Free Migraine Assessment