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Can Fasting Trigger or Relieve Migraines?
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Can Fasting Trigger or Relieve Migraines?

15 min

Does fasting heal migraines—or make them worse? Learn when skipping meals helps, and when it triggers attacks.

00:00
-15:00

Can skipping meals actually trigger your migraines—or could fasting be a tool for healing? In this episode, we explore one of the most controversial topics in the migraine world: fasting. While it’s praised for benefits like reduced inflammation, balanced blood sugar, and mental clarity, fasting can also backfire—especially for women or those already walking a fine line with their health. Drawing on recent studies, real-world client stories, and ancient practices like Ramadan fasting, we break down the biological mechanisms that connect fasting to both headache relief and headache onset. From blood sugar crashes to hormone imbalances, you’ll understand exactly when fasting might help—and when it might make things worse.

What you’ll learn:

  • Why fasting can either reduce or trigger migraines—depending on how and who you are.
  • The science behind fasting headaches, including blood sugar dips, dehydration, cortisol spikes, and caffeine withdrawal.
  • How fasting affects women differently, especially those with hormonal issues, PCOS, or fertility goals.

If you’ve ever skipped a meal and ended up with a pounding head—or wondered if intermittent fasting could help your migraines—this episode gives you the clarity you’ve been craving. Spoiler: fasting is not one-size-fits-all.

Transcript

[00:00]

Can skipping meals actually cause your migraines?

[00:05]

Or could fasting be the key to fewer attacks?

[00:09]

Let's break down the science

[00:11]

and the ancient wisdom behind it.

[00:15]

Migraine Heroes is a podcast for chronic migraine sufferers

[00:19]

who've seen countless doctors with no results.

[00:23]

Learn how to reduce your migraine attacks

[00:25]

without endless medications or constant sacrifices.

[00:30]

Hello, I'm Diane Ducarme.

[00:31]

I've helped over 500 people break free from migraine,

[00:35]

even after suffering for up to 60 years.

[00:38]

My mission in life?

[00:40]

To bring this relief to a million people

[00:42]

using a unique blend of Eastern medicine

[00:45]

and Western science.

[00:49]

In this episode, you will learn why fasting

[00:52]

can both trigger and relieve migraines,

[00:55]

depending on how it's done and what your body needs.

[01:00]

The biological mechanisms behind fasting-induced headaches,

[01:05]

including drop in blood sugar,

[01:07]

dehydration, and stress hormones.

[01:10]

And fasting in women, how fasting can disrupt

[01:13]

or improve female hormonal balance,

[01:16]

affecting negatively or positively menstruation,

[01:21]

fertility, and therefore migraine patterns.

[01:24]

Yesterday, I was on the Migraine Heroes group call.

[01:27]

This is something new, but something I truly love,

[01:29]

because this is where you see transformation happening.

[01:32]

People come with their questions, their wins, their setbacks,

[01:35]

and you get to witness their progress session after session.

[01:38]

And so yesterday, a woman calling in from Vietnam

[01:42]

shared how she had experimented with fasting,

[01:45]

ketogenic diet, and vegetarianism all at the same time.

[01:50]

On paper, each of those approaches sounded healthy

[01:55]

back in time, but in practice,

[01:57]

the combination completely disrupted her digestion

[02:00]

and left her with daily migraines.

[02:04]

Now, she's in the process of unlearning

[02:06]

those sort of healthy habits for her body to heal.

[02:11]

I cannot stress enough that what may suit a person

[02:15]

may not suit another. And that did not suit

[02:18]

that woman in Vietnam who's now battling

[02:21]

with daily migraines.

[02:22]

So let's make the right choices for you.

[02:25]

Let's dive in.

[02:27]

So why do people choose to fast?

[02:30]

Why would anyone willingly go without food

[02:32]

for hours or even days?

[02:34]

Let's look at the benefits of this old practice

[02:37]

and why it's making such a strong comeback today.

[02:40]

There are numerous.

[02:42]

Fasting can help your body become more sensitive to insulin,

[02:46]

which means your blood sugar is better regulated

[02:49]

and your risk of type 2 diabetes goes down.

[02:52]

During fasting, your cells have time to clean up

[02:55]

and repair themselves through a process called autophagy.

[02:59]

It's like hitting the reset button inside your body.

[03:03]

Many people notice that inflammation goes down

[03:06]

when they fast, which is important

[03:08]

because chronic inflammation is linked

[03:10]

to so many modern diseases.

[03:12]

Cholesterol and triglyceride levels can improve

[03:15]

with a regular fasting, supporting heart health.

[03:18]

Mental clarity often increases.

[03:20]

Your brain starts using ketones for fuel,

[03:23]

which some people say gives them sharper, more focused mind.

[03:28]

Over time, it can help regulate appetites

[03:30]

by balancing hormones like ghrelin and leptin.

[03:33]

So you're not just eating because the clock says it's time.

[03:36]

Weight loss is also a common side effect,

[03:39]

especially fat loss because your fasting shifts your body

[03:43]

into a fat burning state.

[03:45]

There's also early research into how fasting might help

[03:48]

reduce the risk of certain cancers,

[03:50]

possibly reducing oxidative stress

[03:53]

and giving the body more time to heal.

[03:55]

And for many people, fasting has a spiritual

[03:58]

or a reflective component.

[04:00]

It creates a space to slow down, check in with yourself

[04:03]

and reconnect to what really matters.

[04:06]

Now that all sounds like a dream, right?

[04:09]

Who wouldn't want any of those benefits?

[04:12]

But in this episode, what I want to do

[04:14]

is I want to ask a deeper question.

[04:17]

Yes, but under what circumstances?

[04:21]

It's easy to list the upsides,

[04:24]

but are they guaranteed for everyone all the time?

[04:27]

So by the end of this episode,

[04:29]

you will know exactly from my work

[04:32]

if fasting is right for you.

[04:34]

Let's take a closer look,

[04:35]

especially at what research says

[04:37]

about fasting and migraines.

[04:40]

So several studies have explored the relationship

[04:44]

between fasting and migraine.

[04:46]

Two interesting studies have been conducted during Ramadan.

[04:50]

Ramadan is a holy month where Muslims

[04:53]

fast from sunrise to sunset.

[04:56]

That's unusual, I will make a religious reference,

[04:59]

and I want to make a really respectful reference here.

[05:01]

It allows us to observe on large scale

[05:04]

the effect of fasting on migraines.

[05:06]

So the first study observed that the frequency

[05:09]

of migraine attacks significantly increased in Ramadan

[05:12]

compared to the preceding month,

[05:14]

and that the number of attacks was reduced

[05:17]

in the later stages of Ramadan

[05:19]

compared to the first 10 days.

[05:22]

The other study found that during Ramadan,

[05:25]

patients experienced on average 9.4 migraine days

[05:29]

compared to 3.7 in the control month,

[05:32]

indicating a significant increase

[05:34]

in migraine frequency during fasting periods.

[05:38]

Another 2023 study indicated that approximately 61%

[05:45]

of individuals practicing intermittent fasting

[05:48]

experienced headaches.

[05:50]

The headaches were attributed to factors

[05:53]

such as hypoglycemia, dehydration, and caffeine withdrawal.

[05:57]

And we're going to talk about these three in particular.

[05:59]

To the point that there's a name for this.

[06:02]

It's called fasting headache.

[06:04]

Now what's a fasting headache?

[06:06]

A fasting headache typically occurs

[06:08]

after not eating for eight hours or more,

[06:11]

and is characterized by mild to moderate non-throwing pain,

[06:14]

often concentrated on the forehead.

[06:17]

This type of headache is linked indeed

[06:19]

to low blood sugar, dehydration, and caffeine withdrawal.

[06:22]

And it can also, that's a very important point,

[06:25]

trigger migraines in those predisposed.

[06:29]

Now let's go into those few mechanisms.

[06:33]

Fasting can indeed lead to several physiological changes

[06:36]

that may trigger migraine.

[06:38]

So we talked about low blood sugar levels, but

[06:40]

those can cause or worsen migraines,

[06:45]

often described as a dull, throbbing pain on the temples.

[06:49]

And that's very similar to mechanisms

[06:51]

that we see in migraine.

[06:53]

Inadequate fluid intake during fasting

[06:55]

can lead to dehydration,

[06:57]

which is a known trigger for headaches.

[06:58]

However, when you don't eat,

[07:01]

your ability to keep the water in

[07:03]

is also decreased, inducing more migraines.

[07:06]

Sudden cessation in caffeine intake during fasting period

[07:09]

can obviously lead to withdrawal headaches.

[07:12]

And then an increase in cortisol level during fasting

[07:14]

may contribute to headache onset.

[07:17]

So let's go back to the positive for a minute.

[07:20]

The benefits have to translate

[07:22]

to some part of the migraine population, right?

[07:25]

So when it comes to migraines,

[07:27]

epilepsy seems to be the winner with fasting.

[07:30]

Fasting, when it induces ketosis specifically,

[07:34]

may offer benefits for people with epilepsy

[07:37]

by reducing neuronal excitability,

[07:40]

enhancing mitochondrial function,

[07:43]

and increasing level of the inhibitory neurotransmitter,

[07:47]

GABA.

[07:49]

These effects can contribute to fewer seizures,

[07:52]

similar to the ketogenic diet

[07:54]

used in drug-resistant epilepsy.

[07:57]

However, fasting can pose also serious risks, right?

[08:02]

That may itself trigger seizures.

[08:05]

So it has to be done with medical supervision.

[08:08]

If this is for you or for one of your children,

[08:11]

please discuss with your doctor

[08:13]

and see if you can find medical support

[08:15]

to start such a fast.

[08:18]

Now, I want to go into women in fasting.

[08:22]

You know, a vast majority of people

[08:23]

who suffer from migraines are women.

[08:25]

So is fasting good for women?

[08:27]

The female endocrine system

[08:29]

is highly responsive to energy availability.

[08:32]

Studies show that extended calorie restriction

[08:35]

or long fasting windows

[08:37]

can disrupt the hypothalamic-pituitary-gonadal axis,

[08:43]

which regulates reproductive hormones.

[08:45]

This disruption may lead to menstrual irregularities,

[08:50]

anovulation, which is no ovulation,

[08:52]

or amenorrhea, which is loss of menstruation,

[08:55]

especially in women with low body fat or high stress level.

[09:00]

And so needless to say,

[09:01]

those will impact migraine patterns.

[09:04]

A 2021 review in Nutrients

[09:06]

highlights that intermittent fasting

[09:08]

may affect the LH and estrogen levels,

[09:11]

potentially impacting fertility,

[09:14]

which is confirmed in animal studies.

[09:17]

Now, I want to share a story,

[09:19]

a French woman living here in New Zealand.

[09:22]

She had very severe endometriosis.

[09:25]

We call her MICA.

[09:26]

She wanted to get pregnant.

[09:27]

She had no menstruation.

[09:29]

I accepted and we worked together.

[09:31]

And after four months,

[09:33]

for the first time, she got her menstruation back

[09:36]

after years of not having them.

[09:38]

Then in WhatsApp, at the time,

[09:40]

it was before the Migraine Heals Chat,

[09:42]

she texts me and she tells me that she's made up her mind

[09:45]

and she's going to go on a full fast.

[09:48]

And luckily it was WhatsApp.

[09:49]

I was able to call her immediately.

[09:51]

And I spent literally, I'm not making this up,

[09:54]

one hour on the phone to explain to her

[09:57]

that that would be a huge mistake

[10:00]

because her body was trusting her

[10:01]

for the first time with the menstruation again,

[10:03]

and that she would undo all of that beautiful work.

[10:06]

In the end, she accepted not to fast.

[10:08]

And that month, that month, she was pregnant.

[10:12]

Basically, her body was telling her,

[10:14]

I'm ready to give it a go.

[10:16]

And so she was ready.

[10:18]

And so I got to meet her daughter

[10:20]

and I got to meet her husband,

[10:22]

who really thanked me for that miracle child.

[10:25]

Here again, there are some women

[10:27]

that will benefit from fasting,

[10:30]

in particular women with PCOS,

[10:33]

what is called polycystic ovary syndrome.

[10:35]

If you have PCOS, there's a good chance

[10:38]

you're dealing with some level of insulin resistance.

[10:41]

And this is where intermittent fasting comes in.

[10:43]

It's going to help your body become more insulin sensitive,

[10:46]

which means better blood sugar control.

[10:48]

And that can lead to a drop in testosterone

[10:50]

and fewer of those super frustrating symptoms

[10:52]

like acne, hair loss, or irregular period.

[10:56]

Over time, fasting may even support

[10:58]

more regular ovulation and hormonal balance.

[11:01]

It has also an impact on inflammation and body composition.

[11:05]

Many women with PCOS struggle with weight

[11:07]

around the midsection and fasting,

[11:09]

especially when combined with an anti-inflammatory diet

[11:12]

can help reduce that visceral fat.

[11:15]

You might also notice better sleep and improve gut health,

[11:18]

especially if you stop eating earlier in the evening.

[11:21]

But here's the thing, even here within PCOS,

[11:25]

it is not one size fits all.

[11:27]

If your body is already under a lot of stress,

[11:30]

or if you are on the leaner side, quite thin,

[11:33]

fasting may do more harm than good.

[11:35]

It can spike cortisol and in some case,

[11:38]

mess with your cycle even more.

[11:40]

This is especially important

[11:42]

if you're actively trying to get pregnant like Micah.

[11:45]

For many women, gentler approaches

[11:47]

like a 12 to 14 hour overnight fast

[11:51]

can still offer big benefits

[11:53]

without disrupting your hormones,

[11:54]

especially if you keep the breakfast

[11:56]

and have a lighter dinner.

[11:59]

So if you're thinking about using fasting

[12:01]

as part of your PCOS toolkit, start slow.

[12:04]

Tune into your cycle, your energy, your stress level.

[12:08]

The goal isn't to restrict,

[12:10]

it's to realign your body with its natural rhythm.

[12:15]

Now, from the five years of working

[12:17]

to create the app of Migraine Heroes, what it is today,

[12:20]

and solving migraines across continents

[12:22]

with all sorts of female and hormonal complications,

[12:26]

we've been able to refine further

[12:28]

who fasting is good for and not so good for.

[12:32]

And so it is beneficial if you lead

[12:34]

or have led a life of excess,

[12:36]

if you've been drinking alcohol for years,

[12:39]

consuming drugs for people who are a bit overweight,

[12:42]

then fasting is a very good tool.

[12:44]

Now, the reality is for most completely different.

[12:48]

A lot of people, the majority of people coming to see us

[12:53]

are saints when it comes to food, habits and lifestyle,

[12:56]

absolute saints.

[12:57]

They are not the excess type.

[12:59]

They put a lot of effort, conscious effort

[13:03]

in choosing the right foods

[13:04]

and being respectful in their environment,

[13:06]

raising their children well and leading really nice homes.

[13:10]

For those, yes, there are some excesses,

[13:13]

but these are mainly medication excesses

[13:15]

and fasting will not remove those excesses,

[13:18]

but rather exacerbate them.

[13:21]

Moreover, skipping meals is a real migraine trigger

[13:25]

and for most, if not all people.

[13:27]

The single most damaging thing I see in women

[13:30]

who for bloating reasons, skip breakfast

[13:33]

and over time make their bloating and migraine worse.

[13:36]

So I'll dedicate a full podcast episodes

[13:39]

to that specific topic in context of perimenopause as well.

[13:42]

So I'm gonna make this short and pragmatic.

[13:45]

You can trust our experience.

[13:47]

We have a library of it.

[13:49]

Fasting is not good for you if you experience

[13:52]

migraines with aura, dizziness, vertigo,

[13:56]

scanty sort of light pink menstruation.

[13:59]

If you experience migraines after your menstruation,

[14:02]

which is a sign of deficiency,

[14:04]

if you experience migraines mid-afternoon,

[14:06]

if you experience migraines in the evening,

[14:09]

if you experience migraines when not eating on time,

[14:11]

if you are thirsty often

[14:13]

or if you're trying to conceive.

[14:15]

Fasting is to be considered for you.

[14:17]

If you have PCOS coupled with excess weight,

[14:21]

if you have epilepsy,

[14:22]

please do that with a qualified health practitioner.

[14:27]

If you have years long of alcohol behind you,

[14:31]

I hope it helps you make the right choices for you.

[14:34]

Those are critical for your brain health.

[14:37]

And remember, every small step you take

[14:41]

moves you closer to freedom.

[14:43]

You are powerful, you are resilient,

[14:46]

and you are never alone.

[14:48]

Keep rising, migraine hero.

[14:55]

Found this episode helpful?

[14:57]

Hit subscribe so you never miss an episode

[14:59]

with the powerful insights and practical tips

[15:02]

for real migraine relief.

Originally published May 2025

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Can Fasting Trigger or Relieve Migraines? | Migraine Heroes